2000199-44-8
2000199-44-8
Chemical Structure
SL-1-73
- CAS No.: 2000199-44-8
- Formula:C20H19N3O5S
- Molecular Weight:413.45
IUPAC Name: N-(2,6-dimethoxypyridin-3-yl)-6-hydroxy-9-methyl-9H-carbazole-3-sulfonamide
InChIKey: UIBOLFBURIUMEU-UHFFFAOYSA-N
SMILES: O=S(NC1=CC=C(OC)N=C1OC)(C2=CC(C3=CC(O)=CC=C3N4C)=C4C=C2)=O
Biological Activity: SL-1-73 is a tubulin ligand. SL-1-73 exhibits antitumor activity against esophageal squamous cell carcinoma (ESCC) both in vitro and in vivo by inhibiting microtubule assembly, inducing G2/M phase cell cycle arrest and apoptosis, and disrupting tumor blood vessels. SL-1-73 can be used for the research of ESCC and other tumors[1].
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SL-1-73 | SL-1-73 is a tubulin ligand. SL-1-73 exhibits antitumor activity against esophageal squamous cell carcinoma (ESCC) both in vitro and in vivo by inhibiting microtubule assembly, inducing G2/M phase cell cycle arrest and apoptosis, and disrupting tumor blood vessels. SL-1-73 can be used for the research of ESCC and other tumors. | |||||||||||||||||||||
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