201487-53-8
201487-53-8
Chemical Structure
BIM-46068
- CAS 番号: 201487-53-8
- Formula:C21H42N4O3S3
- Molecular Weight:494.78
IUPAC Name: methyl ((R)-3-((2S,3S)-2-(((R)-2-amino-3-mercaptopropyl)amino)-3-methylpentyl)-5,5-dimethylthiazolidine-4-carbonyl)-L-methioninate
InChIKey: IRLFXGFBZICNNV-IGKNDFSCSA-N
SMILES: CSCC[C@@H](C(OC)=O)NC([C@H]1N(C[C@@H](NC[C@@H](N)CS)[C@@H](C)CC)CSC1(C)C)=O
Biological Activity: BIM-46068 is a potent, selectively human brain Farnesyltransferase (FTase) inhibitor (IC50 = 91.4 nM). BIM-46068 can specifically inhibit Ras processing in MiaPaCa-2 cancer cells. BIM-46068 can be used for the study of pancreatic cancer[1].
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BIM-46068 | BIM-46068 is a potent, selectively human brain Farnesyltransferase (FTase) inhibitor (IC50 = 91.4 nM). BIM-46068 can specifically inhibit Ras processing in MiaPaCa-2 cancer cells. BIM-46068 can be used for the study of pancreatic cancer. | |||||||||||||||||||||
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