201852-70-2
201852-70-2
Chemical Structure
Gly-Phe-AMC
- CAS No.: 201852-70-2
- Formula:C21H21N3O4
- Molecular Weight:379.41
InChIKey: OXYDLMUFQZNZMD-KRWDZBQOSA-N
SMILES: CC(C1=CC=C(NC([C@@H](NC(CN)=O)CC2=CC=CC=C2)=O)C=C1O3)=CC3=O
Biological Activity: Gly-Phe-AMC is a fluorogenic peptide substrate consisting of a peptide sequence composed of glycine and phenylalanine, linked to the fluorophore AMC. Gly-Phe-AMC also serves as a cathepsin C substrate. Gly-Phe-AMC is widely used to detect the activity of various proteases[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Gly-Phe-AMC | 98.75% | Gly-Phe-AMC is a fluorogenic peptide substrate consisting of a peptide sequence composed of glycine and phenylalanine, linked to the fluorophore AMC. Gly-Phe-AMC also serves as a cathepsin C substrate. Gly-Phe-AMC is widely used to detect the activity of various proteases. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Rebernik M, et al. Interplay between tetrameric structure, enzymatic activity and allosteric regulation of human dipeptidyl-peptidase I. Arch Biochem Biophys. 2019;675:108121. [Content Brief]
- [2]. Horn M, et al. Arginine-based structures are specific inhibitors of cathepsin C. Application of peptide combinatorial libraries. Eur J Biochem. 2000;267(11):3330-3336. [Content Brief]
Keywords
