201852-70-2
201852-70-2
Chemical Structure
Gly-Phe-AMC
- CAS No.: 201852-70-2
- Formula:C21H21N3O4
- Molecular Weight:379.41
InChIKey: OXYDLMUFQZNZMD-KRWDZBQOSA-N
SMILES: CC(C1=CC=C(NC([C@@H](NC(CN)=O)CC2=CC=CC=C2)=O)C=C1O3)=CC3=O
Biological Activity: Gly-Phe-AMC is a fluorogenic peptide substrate consisting of a peptide sequence composed of glycine and phenylalanine, linked to the fluorophore AMC. Gly-Phe-AMC also serves as a cathepsin C substrate. Gly-Phe-AMC is widely used to detect the activity of various proteases[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Gly-Phe-AMC | 99.05% | Gly-Phe-AMC is a fluorogenic peptide substrate consisting of a peptide sequence composed of glycine and phenylalanine, linked to the fluorophore AMC. Gly-Phe-AMC also serves as a cathepsin C substrate. Gly-Phe-AMC is widely used to detect the activity of various proteases. | ||||||||||||||||||||
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Ala-Ala-Phe-AMC | 98.68% | Ala-Ala-Phe-AMC serves as a fluorogenic substrate that exhibits positively charged properties, making it suitable for assessing proteolytic activity. | ||||||||||||||||||||
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Ala-Ala-Phe-AMC TFA | Ala-Ala-Phe-AMC TFA is the TFA salt form for Ala-Ala-Phe-AMC. Ala-Ala-Phe-AMC TFA is a fluorogenic substrate, which is used to for tripeptidyl peptidase II (TPPII) activity determination. | |||||||||||||||||||||
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Suc-Ala-Ala-Phe-AMC | 99.89% | Suc-Ala-Ala-Phe-AMC is a fluorogenic chymotrypsin substrate, can be hydrolyzed by endopeptidase. Suc-Ala-Ala-Phe-AMC has been used in both in vivo assays of the acrosome reaction and in vitro enzyme assays. | ||||||||||||||||||||
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H-Tyr-AMC | H-Tyr-AMC is a fluorogenic substrate for tyrosine aminopeptidases. H-Tyr-AMC is an inhibitor of tobacco and potato hydroxycinnamoyl-CoA:tyramine N-(hydroxycinnamoyl)transferase (THT) with Ki values of 0.72 μM (tobacco) and 0.42 μM (potato). | |||||||||||||||||||||
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Nα-Benzoyl-L-arginine-7-amido-4-methylcoumarin hydrochloride | 99.9% | Nα-Benzoyl-L-arginine-7-amido-4-methylcoumarin hydrochloride is a biochemical assay reagent. | ||||||||||||||||||||
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Glut-Phe-AMC | Glut-Phe-AMC is a fluorescent dye. | |||||||||||||||||||||
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Ala-Phe-Lys-AMC | 99.94% | Ala-Phe-Lys-AMC is a fluorogenic substrate, which can be used for residual plasmin activity assay. | ||||||||||||||||||||
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MeOSuc-Gly-Leu-Phe-AMC | MeOSuc-Gly-Leu-Phe-AMC is a peptide substrate of proteasomal. | |||||||||||||||||||||
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L-Phenylalanine 7-amido-4-methylcoumarin trifluoroacetate | L-Phenylalanine 7-amido-4-methylcoumarin (trifluoroacetate) is a biochemical reagent. | |||||||||||||||||||||
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S-Benzyl-L-cysteine 7-amido-4-methylcoumarin | S-Benzyl-L-cysteine 7-amido-4-methylcoumarin is a biochemical reagent. | |||||||||||||||||||||
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References
- [1]. Rebernik M, et al. Interplay between tetrameric structure, enzymatic activity and allosteric regulation of human dipeptidyl-peptidase I. Arch Biochem Biophys. 2019;675:108121. [Content Brief]
- [2]. Horn M, et al. Arginine-based structures are specific inhibitors of cathepsin C. Application of peptide combinatorial libraries. Eur J Biochem. 2000;267(11):3330-3336. [Content Brief]
