2036074-41-4
2036074-41-4
Chemical Structure
AMPA receptor modulator-1
- CAS No.: 2036074-41-4
- Formula:C16H11ClF3NO2
- Molecular Weight:341.71
IUPAC Name: 5-(2-chloro-6-(trifluoromethoxy)phenyl)-7-methylindolin-2-one
InChIKey: AYAICAKEBFTALD-UHFFFAOYSA-N
SMILES: ClC1=C(C2=CC(C)=C(NC(C3)=O)C3=C2)C(OC(F)(F)F)=CC=C1
Biological Activity: AMPA receptor modulator-1 is a potent, orally active and selective AMPAR regulatory protein TARP γ-8 negative modulator with a pIC50 of 9.7, more selective over GluA1/γ-2 (pIC50=5)[1].
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AMPA receptor modulator-1 | AMPA receptor modulator-1 is a potent, orally active and selective AMPAR regulatory protein TARP γ-8 negative modulator with a pIC50 of 9.7, more selective over GluA1/γ-2 (pIC50=5). | |||||||||||||||||||||
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References
Keywords
