205242-62-2
205242-62-2
Chemical Structure
NAS-181
- CAS No.: 205242-62-2
- Formula:C20H30N2O7S
- Molecular Weight:442.53
IUPAC Name: (R)-2-(((3-(morpholinomethyl)-2H-chromen-8-yl)oxy)methyl)morpholine methanesulfonate
InChIKey: JDFGAOJLDPTWBF-UNTBIKODSA-N
SMILES: CS(=O)(O)=O.[C@H]1(COC2=C3C(C=C(CN4CCOCC4)CO3)=CC=C2)CNCCO1
Biological Activity: NAS-181 is a potent and selective rat 5-hydroxytryptamine1B (r5-HT1B) antagonist with an Ki value of 47 nM. NAS-181 increases the 5-HTP accumulation in rat brain regions[1].
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NAS-181 | NAS-181 is a potent and selective rat 5-hydroxytryptamine1B (r5-HT1B) antagonist with an Ki value of 47 nM. NAS-181 increases the 5-HTP accumulation in rat brain regions. | |||||||||||||||||||||
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