2072057-17-9
2072057-17-9
Chemical Structure
RG7834
Synonym(s): RO 7020322;(S)-RO0321
- CAS No.: 2072057-17-9
- Formula:C22H27NO6
- Molecular Weight:401.45
IUPAC Name: (S)-6-isopropyl-10-methoxy-9-(3-methoxypropoxy)-2-oxo-6,7-dihydro-2H-pyrido[2,1-a]isoquinoline-3-carboxylic acid
InChIKey: KBXLMOYQNDMHQT-KRWDZBQOSA-N
SMILES: O=C(O)C1=CN2[C@@H](CC3=CC(OCCCOC)=C(C=C3C2=CC1=O)OC)C(C)C
Biological Activity: RG7834 (RO 7020322) is a highly selective and orally bioavailable HBV inhibitor, potently inhibits HBV antigens (both HBsAg and HBeAg) and HBV DNA, with IC50s of 2.8, 2.6, and 3.2 nM, respectively, in dHepaRG Cells[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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RG7834 | 99.29% | RG7834 (RO 7020322) is a highly selective and orally bioavailable HBV inhibitor, potently inhibits HBV antigens (both HBsAg and HBeAg) and HBV DNA, with IC50s of 2.8, 2.6, and 3.2 nM, respectively, in dHepaRG Cells. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 1.00
HY-117650(R)-RG7834 -
Similarity Score 0.79
HY-147863HBV-IN-24 -
Similarity Score 0.75
HY-163149AB-452 -
Similarity Score 0.74
HY-145060HBV-IN-13 -
Similarity Score 0.69
HY-145055HBV-IN-11 -
Similarity Score 0.67
HY-156703SHBV-IN-39-d3 -
Similarity Score 0.61
HY-115159Ro 14-9578 -
Similarity Score 0.58
HY-145059HBV-IN-12 -
Similarity Score 0.58
HY-145713GS-8873 -
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