2088930-66-7
2088930-66-7
Chemical Structure
MTC420
- CAS No.: 2088930-66-7
- Formula:C20H16F4N2O
- Molecular Weight:376.35
IUPAC Name: 2-(4-(3,3-difluoropyrrolidin-1-yl)phenyl)-5,7-difluoro-3-methylquinolin-4(1H)-one
InChIKey: FFUXCAUWEZSJRC-UHFFFAOYSA-N
SMILES: FC1=C2C(NC(C3=CC=C(N4CCC(C4)(F)F)C=C3)=C(C)C2=O)=CC(F)=C1
Biological Activity: MTC420 (compound 42a) is a heterocyclic quinolone compound that targets the respiratory chain of Mycobacterium tuberculosis and exhibits antituberculosis activity (Rep Mtb: IC50=525 nM, Wayne Mtb: IC50=76 nM, MDR Mtb: IC50=140 nM)[1].
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MTC420 | MTC420 (compound 42a) is a heterocyclic quinolone compound that targets the respiratory chain of Mycobacterium tuberculosis and exhibits antituberculosis activity (Rep Mtb: IC50=525 nM, Wayne Mtb: IC50=76 nM, MDR Mtb: IC50=140 nM). | |||||||||||||||||||||
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