MTC420
MTC420 (compound 42a) is a heterocyclic quinolone compound that targets the respiratory chain of Mycobacterium tuberculosis and exhibits antituberculosis activity (Rep Mtb: IC50=525 nM, Wayne Mtb: IC50=76 nM, MDR Mtb: IC50=140 nM).
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 2088930-66-7
- Formel: C20H16F4N2O
- Molecular Weight:376.35
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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- Reinheit & Dokumentation
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Help & FAQs
Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
Rep Mtb 525 nM (IC50) |
Wayne Mtb 76 nM (IC50) |
MDR Mtb 140 nM (IC50) |
Chemical Information
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CAS. Nr. 2088930-66-7
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Molecular Weight 376.35
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Formel C20H16F4N2O
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SMILES
FC1=C2C(NC(C3=CC=C(N4CCC(C4)(F)F)C=C3)=C(C)C2=O)=CC(F)=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
MTC420 Related Classifications
HY-116943 Related Classifications
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