2097604-91-4
2097604-91-4
Chemical Structure
AMPA-IN-1
- CAS No.: 2097604-91-4
- Formula:C23H12F2N4O2
- Molecular Weight:414.36
IUPAC Name: 3-methyl-1,5-dihydro-4H-pyrrolo[3,2-c]pyridin-4-one
InChIKey: QAHCTKVCDDSMPT-UHFFFAOYSA-N
SMILES: N#CC1=C(C2=CC3=C(N(C4=CC=CN=C4)C2=O)COC5=C3N=CC(F)=C5)C=CC=C1F
Biological Activity: AMPA-IN-1 is an orally active AMPA receptor inhibitor with an IC50 of 17.70 nM. AMPA-IN-1 inhibits AMPA-induced intracellular calcium influx in rat embryonic cerebral cortical neurons. AMPA-IN-1 exhibits anticonvulsant-related activity in the mouse 6 Hz psychomotor seizure model. AMPA-IN-1 can be used for research on AMPA-mediated diseases, such as epilepsy[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
AMPA-IN-1 | AMPA-IN-1 is an orally active AMPA receptor inhibitor with an IC50 of 17.70 nM. AMPA-IN-1 inhibits AMPA-induced intracellular calcium influx in rat embryonic cerebral cortical neurons. AMPA-IN-1 exhibits anticonvulsant-related activity in the mouse 6 Hz psychomotor seizure model. AMPA-IN-1 can be used for research on AMPA-mediated diseases, such as epilepsy. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
