2111829-84-4

VH032 analogue-1 Chemical Structure
2111829-84-4

Chemical Structure

VH032 analogue-1

  • CAS No.: 2111829-84-4
  • Formula:C23H30N4O5S
  • Molecular Weight:474.57

IUPAC Name: tert-butyl (2-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-2-oxoethyl)carbamate

InChIKey: MLXIIIXJJLAGSR-MSOLQXFVSA-N

SMILES: CC(N=CS1)=C1C(C=C2)=CC=C2CNC([C@H]3N(C[C@@H](C3)O)C(CNC(OC(C)(C)C)=O)=O)=O

Biological Activity: VH032 analogue-1 is a VH032 (HY-120217) analog that acts as a ligand for VHL, recruiting von Hippel-Lindau (VHL) protein. VH032 analogue-1 will remove the protective group under acidic conditions and be directly used for PROTAC molecular synthesis. VH032 analogue-1 is a key intermediate in the synthesis of PROTACs based on VHL ligands.

Cat. No. Product Name Purity Description Pricing
HY-W584527
VH032 analogue-1 VH032 analogue-1 is a VH032 (HY-120217) analog that acts as a ligand for VHL, recruiting von Hippel-Lindau (VHL) protein. VH032 analogue-1 will remove the protective group under acidic conditions and be directly used for PROTAC molecular synthesis. VH032 analogue-1 is a key intermediate in the synthesis of PROTACs based on VHL ligands.
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