2133902-07-3
2133902-07-3
Chemical Structure
BRD4 ligand 2
- CAS No.: 2133902-07-3
- Formula:C20H19N3O2
- Molecular Weight:333.38
IUPAC Name: N-((1s,5s)-5-(3-chloro-4-cyanophenoxy)cyclooctyl)benzamide
InChIKey: XFBRDTMFVAACDR-UHFFFAOYSA-N
SMILES: CC1=NOC(C)=C1C2=CC=C3C(C(NC(N3C)=O)C4=CC=CC=C4)=C2
Biological Activity: BRD4 ligand 2 is a BRD4 BD1 inhibitor with an IC50 of 46.4 nM. BRD4 ligand 2 inhibits the proliferation of lymphoma cells. BRD4 ligand 2 also serves as a target protein ligand for PROTACs, and is used in the synthesis of PROTAC BRD4 Degrader-1 (HY-133131). BRD4 ligand 2 is applicable to research related to lymphoma[1].
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BRD4 ligand 2 | BRD4 ligand 2 is a BRD4 BD1 inhibitor with an IC50 of 46.4 nM. BRD4 ligand 2 inhibits the proliferation of lymphoma cells. BRD4 ligand 2 also serves as a target protein ligand for PROTACs, and is used in the synthesis of PROTAC BRD4 Degrader-1 (HY-133131). BRD4 ligand 2 is applicable to research related to lymphoma. | |||||||||||||||||||||
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