2141978-86-9
Chemical Structure
K22
- CAS No.: 2141978-86-9
- Formula:C27H25BrN2O3
- Molecular Weight:505.40
IUPAC Name: (Z)-N-(3-(4-(4-bromophenyl)-4-hydroxypiperidin-1-yl)-3-oxo-1-phenylprop-1-en-2-yl)benzamide
InChIKey: CMBUSPXASRNJHI-CLCOLTQESA-N
SMILES: O=C(N/C(C(N1CCC(O)(C2=CC=C(Br)C=C2)CC1)=O)=C\C3=CC=CC=C3)C4=CC=CC=C4
Biological Activity: K22 is an anti-Coronaviral compound. K22 reduces double-stranded RNA. K22 displays antiviral activity beyond the Coronavirinae subfamily, namely against nidoviruses of the Torovirinae subfamily (EToV and WBV) and members of the Arteriviridae family (PRRSV, EAV). K22 displays antiviral activity against HCoV-229E[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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K22 | 98.46% | K22 is an anti-Coronaviral compound. K22 reduces double-stranded RNA. K22 displays antiviral activity beyond the Coronavirinae subfamily, namely against nidoviruses of the Torovirinae subfamily (EToV and WBV) and members of the Arteriviridae family (PRRSV, EAV). K22 displays antiviral activity against HCoV-229E. | ||||||||||||||||||||
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- [1]. Lundin A, et al. Targeting membrane-bound viral RNA synthesis reveals potent inhibition of diverse coronaviruses including the middle East respiratory syndrome virus. PLoS Pathog. 2014;10(5):e1004166. Published 2014 May 29. [Content Brief]
- [2]. Rappe JCF, et al. Antiviral activity of K22 against members of the order Nidovirales. Virus Res. 2018;246:28-34. [Content Brief]
Keywords
