2146095-85-2
Chemical Structure
SHIN1
Synonym(s): RZ-2994
- CAS No.: 2146095-85-2
- Formula:C24H24N4O2
- Molecular Weight:400.47
IUPAC Name: 6-amino-4-(5-(hydroxymethyl)-[1,1'-biphenyl]-3-yl)-4-isopropyl-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
InChIKey: VVVOFJZXKJKHTD-UHFFFAOYSA-N
SMILES: OCC1=CC(C2=CC=CC=C2)=CC(C3(C(C(C)=NN4)=C4OC(N)=C3C#N)C(C)C)=C1
Biological Activity: SHIN1 (RZ-2994) is a human serine hydroxymethyltransferse 1 and 2 (SHMT1/2) inhibitor with IC50s of 5 and 13 nM, respectively, in an in vitro assay.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
SHIN1 | 98.63% | SHIN1 (RZ-2994) is a human serine hydroxymethyltransferse 1 and 2 (SHMT1/2) inhibitor with IC50s of 5 and 13 nM, respectively, in an in vitro assay. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
-
Similarity Score 1.00
HY-112066A(+)-SHIN1 -
Similarity Score 1.00
HY-112066B(-)-SHIN1 -
Similarity Score 0.72
HY-134978(Rac)-SHIN2 -
Similarity Score 0.72
HY-134978A(+)SHIN2 -
Similarity Score 0.64
HY-129226SHMT-IN-2 -
Similarity Score 0.58
HY-129651SHMT-IN-1 -
Similarity Score 0.51
HY-180895Y207–5465 -
Similarity Score 0.50
HY-147944Antimicrobial agent-4 -
Similarity Score 0.49
HY-12873RBC8 -
Explore the MedChemAI to find more analogs