215655-21-3
215655-21-3
Chemical Structure
ICT5040
- CAS No.: 215655-21-3
- Formula:C10H8F3N3OS
- Molecular Weight:275.25
IUPAC Name: 2-(2-methyl-6-(trifluoromethyl)pyridin-3-yl)-5-(methylthio)-1,3,4-oxadiazole
InChIKey: AOFNOJJLNOMAHQ-UHFFFAOYSA-N
SMILES: FC(C1=CC=C(C2=NN=C(SC)O2)C(C)=N1)(F)F
Biological Activity: ICT5040 is a small molecule CXCR4 antagonist (IC50=3.8 μM). ICT5040 inhibits CXCL12-mediated proliferation and migration, and suppresses CXCL12-induced intracellular calcium mobilisation in U87 glioma cells[1].
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ICT5040 | ICT5040 is a small molecule CXCR4 antagonist (IC50=3.8 μM). ICT5040 inhibits CXCL12-mediated proliferation and migration, and suppresses CXCL12-induced intracellular calcium mobilisation in U87 glioma cells. | |||||||||||||||||||||
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