2185857-97-8
Chemical Structure
Ebvaciclib
Synonym(s): PF-06873600
- CAS No.: 2185857-97-8
- Formula:C20H27F2N5O4S
- Molecular Weight:471.52
IUPAC Name: 6-(difluoromethyl)-8-((1R,2R)-2-hydroxy-2-methylcyclopentyl)-2-((1-(methylsulfonyl)piperidin-4-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one
InChIKey: QIEKHLDZKRQLLN-FOIQADDNSA-N
SMILES: O=C1N([C@H]2[C@](O)(CCC2)C)C3=NC(NC4CCN(CC4)S(C)(=O)=O)=NC=C3C=C1C(F)F
Biological Activity: PF-06873600 is a selective and orally bioavailable inhibitor of cyclin-dependent kinase (CDK), with Ki values of 0.09 nM, 0.13 nM and 0.16 nM for CDK2, CDK4 and CDK6, respectively. PF-06873600 has potential antineoplastic activity[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Ebvaciclib | 99.91% | PF-06873600 is a selective and orally bioavailable inhibitor of cyclin-dependent kinase (CDK), with Ki values of 0.09 nM, 0.13 nM and 0.16 nM for CDK2, CDK4 and CDK6, respectively. PF-06873600 has potential antineoplastic activity. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
