21886-12-4
21886-12-4
Chemical Structure
PNU112455A hydrochloride
- CAS No.: 21886-12-4
- Formula:C10H12ClN5O2S
- Molecular Weight:301.75
IUPAC Name: 4-((6-aminopyrimidin-4-yl)amino)benzenesulfonamide hydrochloride
InChIKey: XBXQRCJKDCEQBS-UHFFFAOYSA-N
SMILES: O=S(C1=CC=C(NC2=NC=NC(N)=C2)C=C1)(N)=O.[H]Cl
Biological Activity: PNU112455A hydrochloride is an ATP-competitive CDK2 and CDK5 inhibitor. PNU112455A hydrochloride binds to the ATP site of CDK2 and CDK5 with Kms of 3.6 and 3.2 μM, respectively[1].
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PNU112455A hydrochloride | 99.56% | PNU112455A hydrochloride is an ATP-competitive CDK2 and CDK5 inhibitor. PNU112455A hydrochloride binds to the ATP site of CDK2 and CDK5 with Kms of 3.6 and 3.2 μM, respectively. | ||||||||||||||||||||
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