1. Cell Cycle/DNA Damage
  2. CDK
  3. PNU112455A hydrochloride

PNU112455A hydrochloride 

Cat. No.: HY-112468 Purity: 99.62%
Handling Instructions

PNU112455A hydrochloride is an ATP-competitive CDK2 and CDK5 inhibitor. PNU112455A hydrochloride binds to the ATP site of CDK2 and CDK5 with Kms of 3.6 and 3.2 μM, respectively.

For research use only. We do not sell to patients.

PNU112455A hydrochloride Chemical Structure

PNU112455A hydrochloride Chemical Structure

CAS No. : 21886-12-4

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Description

PNU112455A hydrochloride is an ATP-competitive CDK2 and CDK5 inhibitor. PNU112455A hydrochloride binds to the ATP site of CDK2 and CDK5 with Kms of 3.6 and 3.2 μM, respectively[1].

IC50 & Target[1]

CDK2

3.6 μM (Km)

CDK5

3.2 μM (Km)

Molecular Weight

301.75

Formula

C₁₀H₁₂ClN₅O₂S

CAS No.

21886-12-4

SMILES

O=S(C1=CC=C(NC2=NC=NC(N)=C2)C=C1)(N)=O.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References
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Keywords:

PNU112455ACDKCyclin dependent kinaseATPsiteanticooperativecompetitiveAlzheimer'sdiseaseInhibitorinhibitorinhibit

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Product name:
PNU112455A hydrochloride
Cat. No.:
HY-112468
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