219581-36-9
Chemical Structure
Alvameline maleate
Synonym(s): Lu 25-109 maleate
- CAS No.: 219581-36-9
- Formula:C13H19N5O4
- Molecular Weight:309.32
IUPAC Name: 5-(2-ethyl-2H-tetrazol-5-yl)-1-methyl-1,2,3,6-tetrahydropyridine maleate
InChIKey: YKFYFAAWVQGVTP-BTJKTKAUSA-N
SMILES: OC(/C=C\C(O)=O)=O.CCN1N=C(C2=CCCN(C)C2)N=N1
Biological Activity: Alvameline (Lu 25-109) maleate is a partial agonist of M1 and an antagonist of M2/M3. Alvameline maleate competitively antagonizes contractions induced by ammonium chloride (HY-Y1269) and electrical field stimulation in human detrusor muscle, indicating its potential application in regulating bladder function. Additionally, alvameline maleate can improve cognitive function following traumatic brain injury in rats[1].
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Alvameline maleate | Alvameline (Lu 25-109) maleate is a partial agonist of M1 and an antagonist of M2/M3. Alvameline maleate competitively antagonizes contractions induced by ammonium chloride (HY-Y1269) and electrical field stimulation in human detrusor muscle, indicating its potential application in regulating bladder function. Additionally, alvameline maleate can improve cognitive function following traumatic brain injury in rats. | |||||||||||||||||||||
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Keywords
