219861-53-7
219861-53-7
Chemical Structure
(R)-Citalopram oxalate
- CAS No.: 219861-53-7
- Formula:C22H23FN2O5
- Molecular Weight:414.43
IUPAC Name: (R)-1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile oxalate
InChIKey: KTGRHKOEFSJQNS-VEIFNGETSA-N
SMILES: OC(C(O)=O)=O.CN(C)CCC[C@@]1(C2=CC=C(C=C2)F)C3=CC=C(C#N)C=C3CO1
Biological Activity: (R)-Citalopram oxalate, a R-(-) enantiomers of Citalopram (HY-121203), is a serotonin reuptake inhibitor. (R)-Citalopram oxalate is at least 20-fold weaker than S-citalopram (HY-14258) as inhibitor of the 5-HT transporter (SERT). (R)-Citalopram oxalate can be used for research of depression[1][2][3].
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(R)-Citalopram oxalate | 99.52% | (R)-Citalopram oxalate, a R-(-) enantiomers of Citalopram (HY-121203), is a serotonin reuptake inhibitor. (R)-Citalopram oxalate is at least 20-fold weaker than S-citalopram (HY-14258) as inhibitor of the 5-HT transporter (SERT). (R)-Citalopram oxalate can be used for research of depression. | ||||||||||||||||||||
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(R)-Citalopram oxalate (Standard) | ≥98% | (R)-Citalopram oxalate (Standard) is the analytical standard of (R)-Citalopram oxalate. This product is intended for research and analytical applications. (R)-Citalopram oxalate, a R-(-) enantiomers of Citalopram (HY-121203), is a serotonin reuptake inhibitor. (R)-Citalopram oxalate is at least 20-fold weaker than S-citalopram (HY-14258) as inhibitor of the 5-HT transporter (SERT). (R)-Citalopram oxalate can be used for research of depression. | ||||||||||||||||||||
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(R)-Citalopram-d4 oxalate | (R)-Citalopram-d4 (oxalate) is deuterium labeled (R)-Citalopram Oxalate. (R)-Citalopram oxalate, a R-(-) enantiomers of Citalopram (HY-121203), is a serotonin reuptake inhibitor. (R)-Citalopram oxalate is at least 20-fold weaker than S-citalopram (HY-14258) as inhibitor of the 5-HT transporter (SERT). (R)-Citalopram oxalate can be used for research of depression. | |||||||||||||||||||||
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References
- [1]. Bezchlibnyk-Butler K, et al. Citalopram--a review of pharmacological and clinical effects. J Psychiatry Neurosci. 2000 May;25(3):241-54. [Content Brief]
- [2]. Stórustovu Sí, et al. R-citalopram functionally antagonises escitalopram in vivo and in vitro: evidence for kinetic interaction at the serotonin transporter. Br J Pharmacol. 2004 May;142(1):172-80. [Content Brief]
- [3]. Sánchez C. The pharmacology of citalopram enantiomers: the antagonism by R-citalopram on the effect of S-citalopram. Basic Clin Pharmacol Toxicol. 2006 Aug;99(2):91-5. [Content Brief]
