2227008-67-3
2227008-67-3
Chemical Structure
93-O17S
- CAS No.: 2227008-67-3
- Formula:C44H83N3O4S2
- Molecular Weight:782.28
IUPAC Name: bis(2-(tetradecylthio)ethyl) 3,3'-((3-(1H-imidazol-1-yl)propyl)azanediyl)dipropionate
InChIKey: OLOIOPYNTGMAAP-UHFFFAOYSA-N
SMILES: O=C(CCN(CCCN1C=NC=C1)CCC(OCCSCCCCCCCCCCCCCC)=O)OCCSCCCCCCCCCCCCCC
Biological Activity: 93-O17S is an ionizable lipid. 93-O17S is involved in the construction of LNP. 93-O17S can achieve mRNA delivery to the spleen[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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93-O17S | 98.0% | 93-O17S is an ionizable lipid. 93-O17S is involved in the construction of LNP. 93-O17S can achieve mRNA delivery to the spleen. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.83
HY-W59817893-O17O -
Similarity Score 0.77
HY-1605539322-O16B -
Similarity Score 0.69
HY-153186LNP Lipid-3 -
Similarity Score 0.66
HY-159711PPPDA-O16B -
Similarity Score 0.66
HY-W59053180-O16B -
Similarity Score 0.64
HY-15969980-O18 -
Similarity Score 0.62
HY-15644880-O14B -
Similarity Score 0.62
HY-W274378RDistearyl thiodipropionate (Standard) -
Similarity Score 0.61
HY-149156Lipid C24 -
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References
- [1]. Omo-Lamai S, et al. Lipid Nanoparticle-Associated Inflammation is Triggered by Sensing of Endosomal Damage: Engineering Endosomal Escape Without Side Effects. bioRxiv [Preprint]. 2024 Apr 18:2024.04.16.589801. [Content Brief]
- [2]. Delehedde C, et al. Intracellular Routing and Recognition of Lipid-Based mRNA Nanoparticles. Pharmaceutics. 2021 Jun 24;13(7):945. [Content Brief]
