2234897-35-7
2234897-35-7
Chemical Structure
Grp94 Inhibitor-1
- CAS No.: 2234897-35-7
- Formula:C22H28N2O2
- Molecular Weight:352.47
IUPAC Name: 4-(((1r,4r)-4-hydroxycyclohexyl)amino)-4'-isopropyl-[1,1'-biphenyl]-3-carboxamide
InChIKey: JMGDXIHGWTVBMX-WGSAOQKQSA-N
SMILES: O=C(C1=CC(C2=CC=C(C(C)C)C=C2)=CC=C1N[C@H]3CC[C@H](O)CC3)N
Biological Activity: Grp94 Inhibitor-1 is a potent, selective Grp94 inhibitor with an IC50 value of 2 nM, and over 1000-fold selectivity to Grp94 against Hsp90α[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Grp94 Inhibitor-1 | 98.99% | Grp94 Inhibitor-1 is a potent, selective Grp94 inhibitor with an IC50 value of 2 nM, and over 1000-fold selectivity to Grp94 against Hsp90α. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.50
HY-146315AChE/BChE-IN-6 -
Similarity Score 0.50
![2'-Amino-5'-isopropyl-[1,1':3',1''-terphenyl]-4,4''-dicarboxylic acid Chemical Structure](//file.medchemexpress.com/product_pic/hy-w112575.gif)
HY-W1125752'-Amino-5'-isopropyl-[1,1':3',1''-terphenyl]-4,4''-dicarboxylic acid -
Similarity Score 0.50
HY-183887PD-L1-IN-11 -
Similarity Score 0.49
![3-Amino-[1,1'-biphenyl]-4,4'-dicarboxylic acid Chemical Structure](//file.medchemexpress.com/product_pic/hy-w249816.gif)
HY-W2498163-Amino-[1,1'-biphenyl]-4,4'-dicarboxylic acid -
Similarity Score 0.48
HY-125533TXA497 -
Similarity Score 0.48
HY-130179RC-33 hydrochloride -
Similarity Score 0.48
HY-W087195Biprofen -
Similarity Score 0.48
![4,4'-Diamino-[1,1'-biphenyl]-3,3'-dicarboxylic acid Chemical Structure](//file.medchemexpress.com/product_pic/hy-w298102.gif)
HY-W2981024,4'-Diamino-[1,1'-biphenyl]-3,3'-dicarboxylic acid -
Similarity Score 0.48
![3,3''-Diamino-[1,1':4',1''-terphenyl]-4,4''-dicarboxylicacid Chemical Structure](//file.medchemexpress.com/product_pic/hy-w113021.gif)
HY-W1130213,3''-Diamino-[1,1':4',1''-terphenyl]-4,4''-dicarboxylicacid -
Explore the MedChemAI to find more analogs
![2'-Amino-5'-isopropyl-[1,1':3',1''-terphenyl]-4,4''-dicarboxylic acid Chemical Structure](http://file.medchemexpress.com/product_pic/hy-w112575.gif)
![3-Amino-[1,1'-biphenyl]-4,4'-dicarboxylic acid Chemical Structure](http://file.medchemexpress.com/product_pic/hy-w249816.gif)
![4,4'-Diamino-[1,1'-biphenyl]-3,3'-dicarboxylic acid Chemical Structure](http://file.medchemexpress.com/product_pic/hy-w298102.gif)
![3,3''-Diamino-[1,1':4',1''-terphenyl]-4,4''-dicarboxylicacid Chemical Structure](http://file.medchemexpress.com/product_pic/hy-w113021.gif)
