2237942-08-2
2237942-08-2
Chemical Structure
MC180295
Synonym(s): (rel)-MC180295
- CAS No.: 2237942-08-2
- Formula:C17H18N4O3S
- Molecular Weight:358.41
IUPAC Name: (4-amino-2-(((1S,2S,4R)-bicyclo[2.2.1]heptan-2-yl)amino)thiazol-5-yl)(2-nitrophenyl)methanone
InChIKey: JRNXAQINDCOHGS-SCVCMEIPSA-N
SMILES: NC1=C(C(C2=CC=CC=C2[N+]([O-])=O)=O)SC(N[C@@H]3[C@H](C4)CC[C@H]4C3)=N1
Biological Activity: MC180295 ((rel)-MC180295) is a potent and selective CDK9-Cyclin T1 inhibitor, with an IC50 of 5 nM, at least 22-fold more selective for CDK9 over other CDKs. MC180295 also inhibits GSK-3α and GSK-3β. MC180295 ((rel)-MC180295) has potent anti-tumor effect[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
MC180295 | 98.07% | MC180295 ((rel)-MC180295) is a potent and selective CDK9-Cyclin T1 inhibitor, with an IC50 of 5 nM, at least 22-fold more selective for CDK9 over other CDKs. MC180295 also inhibits GSK-3α and GSK-3β. MC180295 ((rel)-MC180295) has potent anti-tumor effect. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
