2247168-13-2
2247168-13-2
Chemical Structure
DS42450411
- CAS No.: 2247168-13-2
- Formula:C22H28N4
- Molecular Weight:348.48
IUPAC Name: 8-(1-((1r,4r)-4-aminocyclohexyl)vinyl)-5,5-dimethyl-5,6-dihydrobenzo[h]quinazolin-4-amine
InChIKey: ADLAJVKSIHBUEZ-CZIWCDLHSA-N
SMILES: NC1=C2C(C)(C)CC3=CC(C([C@H]4CC[C@H](N)CC4)=C)=CC=C3C2=NC=N1
Biological Activity: DS42450411 is an orally active hepcidin production inhibitor with an IC50 of 32 nM. DS42450411 in an acute inflammatory mouse model induced by IL-6, DS42450411 significantly reduces serum hepcidin levels. DS42450411 can be used for studying iron homeostasis[1].
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DS42450411 | DS42450411 is an orally active hepcidin production inhibitor with an IC50 of 32 nM. DS42450411 in an acute inflammatory mouse model induced by IL-6, DS42450411 significantly reduces serum hepcidin levels. DS42450411 can be used for studying iron homeostasis. | |||||||||||||||||||||
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