2250132-99-9

JTP-117968 Chemical Structure
2250132-99-9

Chemical Structure

JTP-117968

  • CAS No.: 2250132-99-9
  • Formula:C31H31F3N2O2
  • Molecular Weight:520.59

IUPAC Name: (4b'S,7'R,8a'S)-4b'-benzyl-7'-hydroxy-N-(2-methylpyridin-3-yl)-7'-(trifluoromethyl)-4b',6',7',8',8a',10'-hexahydro-5'H-spiro[cyclopropane-1,9'-phenanthrene]-2'-carboxamide

InChIKey: VOOOFTVRKCSOIU-NPBSGPTKSA-N

SMILES: O=C(C(C=C1C2)=CC=C1[C@]3(CC4=CC=CC=C4)CC[C@@](C(F)(F)F)(O)C[C@@]3([H])C52CC5)NC6=CC=CN=C6C

Biological Activity: JTP-117968, a novel selective glucocorticoid receptor modulator (a non-steroidal SGRM, IC50 of 6.8 nM), exhibits improved transrepression/transactivation dissociation[1].

Cat. No. Product Name Purity Description Pricing
HY-125265
JTP-117968 JTP-117968, a novel selective glucocorticoid receptor modulator (a non-steroidal SGRM, IC50 of 6.8 nM), exhibits improved transrepression/transactivation dissociation.
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