2250313-14-3
Chemical Structure
Influenza A virus-IN-1
- CAS No.: 2250313-14-3
- Formula:C27H20F6N2O3
- Molecular Weight:534.45
IUPAC Name: ethyl 5-oxo-2-phenyl-1-(4-(trifluoromethyl)phenyl)-4-((4-(trifluoromethyl)phenyl)amino)-2,5-dihydro-1H-pyrrole-3-carboxylate
InChIKey: IRTZGBURXBOHPW-UHFFFAOYSA-N
SMILES: O=C(C1=C(NC2=CC=C(C(F)(F)F)C=C2)C(N(C3=CC=C(C(F)(F)F)C=C3)C1C4=CC=CC=C4)=O)OCC
Biological Activity: Influenza A virus-IN-1 is a dihydropyrrolidones derivative and is a potent inhibitor against wide subtypes of influenza A virus (IAV) with IC50 values from 3.11 μM to 7.13 μM. Influenza A virus-IN-1 efficiently inhibits replication of IAV, up-regulates the expression of key antiviral cytokines IFN-β and antiviral protein MxA[1].
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Influenza A virus-IN-1 | 99.30% | Influenza A virus-IN-1 is a dihydropyrrolidones derivative and is a potent inhibitor against wide subtypes of influenza A virus (IAV) with IC50 values from 3.11 μM to 7.13 μM. Influenza A virus-IN-1 efficiently inhibits replication of IAV, up-regulates the expression of key antiviral cytokines IFN-β and antiviral protein MxA. | ||||||||||||||||||||
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