2252162-81-3
2252162-81-3
Chemical Structure
Aβ/tau aggregation-IN-1
- CAS No.: 2252162-81-3
- Formula:C25H21IN2O
- Molecular Weight:492.35
IUPAC Name: (E)-9-amino-10-methyl-2-(naphthalen-1-ylmethylene)-1-oxo-1,2,3,4-tetrahydroacridin-10-ium iodide
InChIKey: ZPWPPSSEAGEKIT-FLNCGGNMSA-N
SMILES: NC1=C2C(CC/C(C2=O)=C\C3=CC=CC4=C3C=CC=C4)=[N+](C5=CC=CC=C51)C.[I-]
Biological Activity: Aβ/tau aggregation-IN-1 is a potent Aβ1-42 β-sheets formation and tau aggregation inhibitor. The KD values of Aβ/tau aggregation-IN-1 with Aβ1-42 and tau are 160 μM and 337 μM, respectively. Aβ/tau aggregation-IN-1 can permeate the blood-brain barrier[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Aβ/tau aggregation-IN-1 | 98.10% | Aβ/tau aggregation-IN-1 is a potent Aβ1-42 β-sheets formation and tau aggregation inhibitor. The KD values of Aβ/tau aggregation-IN-1 with Aβ1-42 and tau are 160 μM and 337 μM, respectively. Aβ/tau aggregation-IN-1 can permeate the blood-brain barrier. | ||||||||||||||||||||
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References
Keywords
