226929-39-1
226929-39-1
Chemical Structure
LB42708
- CAS No.: 226929-39-1
- Formula:C30H27BrN4O2
- Molecular Weight:555.47
IUPAC Name: (1-((1-(4-bromobenzyl)-1H-imidazol-5-yl)methyl)-4-(naphthalen-1-yl)-1H-pyrrol-3-yl)(morpholino)methanone
InChIKey: GUUIRIMAQGOLHT-UHFFFAOYSA-N
SMILES: O=C(C1=CN(CC2=CN=CN2CC3=CC=C(Br)C=C3)C=C1C4=C5C=CC=CC5=CC=C4)N6CCOCC6
Biological Activity: LB42708 is a potent, selective and orally active farnesyltransferase inhibitor. LB42708 inhibits farnesylation of H-Ras, N-Ras and K-Ras4B with IC50s of 0.8 nM, 1.2 nM and 2.0 nM, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
LB42708 | 98.02% | LB42708 is a potent, selective and orally active farnesyltransferase inhibitor. LB42708 inhibits farnesylation of H-Ras, N-Ras and K-Ras4B with IC50s of 0.8 nM, 1.2 nM and 2.0 nM, respectively. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.74
HY-120763LB42908 -
Similarity Score 0.48
HY-144873AVJ16 -
Similarity Score 0.47
HY-120542SR 1824 -
Similarity Score 0.46
HY-153450JBI-589 -
Similarity Score 0.46
HY-106123Pomisartan -
Similarity Score 0.46
HY-155158Anticancer agent 147 -
Similarity Score 0.46
HY-112424Tinodasertib -
Similarity Score 0.45
HY-145169AZ194 -
Similarity Score 0.45
HY-12369GGTI-2133 -
Explore the MedChemAI to find more analogs
