2271229-98-0
2271229-98-0
Chemical Structure
HDAC6-IN-86
- CAS No.: 2271229-98-0
- Formula:C21H18N2O3S
- Molecular Weight:378.44
InChIKey: WIQDMYVWEJAYQM-UHFFFAOYSA-N
SMILES: O=C(NO)C(C=C1)=CC=C1CN2C3=CC=CC=C3SC4=C2C=C(OC)C=C4
Biological Activity: HDAC6-IN-86 is a histone deacetylase 6 (HDAC6) inhibitor with an IC50 of 74 nM, and it exhibits high selectivity for HDAC1. HDAC6-IN-86 induces cell apoptosis, triggers G2/M phase cell cycle arrest, and inhibits the proliferation of glioma cells. HDAC6-IN-86 can be used for the research of glioblastoma multiforme (GBM)[1].
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HDAC6-IN-86 | HDAC6-IN-86 is a histone deacetylase 6 (HDAC6) inhibitor with an IC50 of 74 nM, and it exhibits high selectivity for HDAC1. HDAC6-IN-86 induces cell apoptosis, triggers G2/M phase cell cycle arrest, and inhibits the proliferation of glioma cells. HDAC6-IN-86 can be used for the research of glioblastoma multiforme (GBM). | |||||||||||||||||||||
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References
Keywords
