2300178-70-3
2300178-70-3
Chemical Structure
Toxoflavin-13C4
Synonym(s): Xanthothricin-13C4; Toxoflavine-13C4; PKF-118-310-13C4
- CAS No.: 2300178-70-3
- Formula:C313C4H6N5O2
- Molecular Weight:196.13
IUPAC Name: 1,6-dimethyl-3l3-pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione-3,4a,5,8a-13C4
InChIKey: IYNSLJYLYGYGNH-PQVJJBODSA-N
SMILES: O=[13C]([13C]1=N[13C]=NN(C)[13C]1=N2)N(C)C2=O
Biological Activity: Toxoflavin-13C4 is the 13C-labeled Toxoflavin. Toxoflavin (Xanthothricin) is an antagonist of transcription factor 4 (TCF4)/β-catenin complex, also acts as an inhibitor of KDM4A, with antitumor activity[1][2]. Antibiotic properties.
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Toxoflavin-13C4 | Toxoflavin-13C4 is the 13C-labeled Toxoflavin. Toxoflavin (Xanthothricin) is an antagonist of transcription factor 4 (TCF4)/β-catenin complex, also acts as an inhibitor of KDM4A, with antitumor activity. Antibiotic properties. | |||||||||||||||||||||
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Toxoflavin (Standard) | ≥98% | Toxoflavin (Standard) is the analytical standard of Toxoflavin. This product is intended for research and analytical applications. Toxoflavin (Xanthothricin) is an antagonist of transcription factor 4 (TCF4)/β-catenin complex, also acts as an inhibitor of KDM4A, with antitumor and antibiotic activity. | ||||||||||||||||||||
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Toxoflavin | 99.88% | Toxoflavin (Xanthothricin) is an antagonist of transcription factor 4 (TCF4)/β-catenin complex, also acts as an inhibitor of KDM4A, with antitumor and antibiotic activity. | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Wei W, et al. Small molecule antagonists of Tcf4/beta-catenin complex inhibit the growth of HCC cells in vitro and in vivo. Int J Cancer. 2010 May 15;126(10):2426-36. [Content Brief]
