233691-67-3
Chemical Structure
Boc-Lys(Ac)-AMC
- CAS No.: 233691-67-3
- Formula:C23H31N3O6
- Molecular Weight:445.51
IUPAC Name: tert-butyl (S)-(6-acetamido-1-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-1-oxohexan-2-yl)carbamate
InChIKey: SUTRDULVNIPNLW-SFHVURJKSA-N
SMILES: CC(C(C(O1)=C2)=CC=C2NC([C@H](CCCCNC(C)=O)NC(OC(C)(C)C)=O)=O)=CC1=O
Biological Activity: Boc-Lys(Ac)-AMC is a cell-permeable fluorometric HDAC substrate (Ex/Em = 355 nm/460 nm)[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Boc-Lys(Ac)-AMC | 98.59% | Boc-Lys(Ac)-AMC is a cell-permeable fluorometric HDAC substrate (Ex/Em = 355 nm/460 nm). | ||||||||||||||||||||
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- [1]. Reddy DS, et al. Measuring Histone Deacetylase Inhibition in the Brain. Curr Protoc Pharmacol. 2018 Jun;81(1):e41. [Content Brief]
- [2]. Ueki N, et al. Selective cancer targeting with prodrugs activated by histone deacetylases and a tumour-associated protease. Nat Commun. 2013;4:2735. [Content Brief]
Keywords