235090-14-9
Chemical Structure
Strevertene A
Synonym(s): (-)-Strevertene A
- CAS No.: 235090-14-9
- Formula:C31H48O10
- Molecular Weight:580.71
InChIKey: ALFUZUYJAXAEKE-LCQSMXBUSA-N
SMILES: O[C@H](C[C@H](O)[C@H]1C)C[C@@H](O)CCC[C@@H](O)C[C@@H](O)[C@@H](C(O)=O)[C@H](O)/C=C/C=C/C=C/C=C/C=C\[C@H](C)[C@@H](C)OC1=O
Biological Activity: Strevertene A ((-)-Strevertene A) (Compound 1), a pentaene macrolide, is a microbial secondary metabolite. Strevertene A is an antibiotic and has a potent antifungal activity. Strevertene A significantly inhibits the mycelial growth of phytopathogenic fungi (such as Alternaria mali, Aspergillus oryzae and Cylindrocarpon destructans) with IC50s of 4-16 μg/mL. Strevertenes A can strongly prevent Fusarium wilt development on tomato plants[1][2].
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Strevertene A | Strevertene A ((-)-Strevertene A) (Compound 1), a pentaene macrolide, is a microbial secondary metabolite. Strevertene A is an antibiotic and has a potent antifungal activity. Strevertene A significantly inhibits the mycelial growth of phytopathogenic fungi (such as Alternaria mali, Aspergillus oryzae and Cylindrocarpon destructans) with IC50s of 4-16 μg/mL. Strevertenes A can strongly prevent Fusarium wilt development on tomato plants. | |||||||||||||||||||||
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- [1]. Bonini C, et al. A first convergent synthesis of the polyolic fragment of the antifungal pentaene macrolide strevertene A[J]. Tetrahedron Letters, 2008, 49(38): 5455-5457.
- [2]. Kim JD, et al. Disease control effect of strevertenes produced by Streptomyces psammoticus against tomato fusarium wilt. J Agric Food Chem. 2011 Mar 9;59(5):1893-9. [Content Brief]
Keywords