2364572-10-9
Chemical Structure
Vodudeutentan sodium
- CAS No.: 2364572-10-9
- Formula:C34H48D2N5NaO7
- Molecular Weight:665.79
InChIKey: QCVIFBRTTLMEOV-ZOHSNMQTSA-M
SMILES: O=C(N1[C@@H](CCC[C@@H]1C[2H])C[2H])N[C@@H](CC(C)(C)C)C(N[C@@H](C(N[C@@H](C(O[Na])=O)CCCC)=O)CC2=CN(C(OC)=O)C3=CC=CC=C23)=O
Biological Activity: Vodudeutentan sodium is a deuterated endothelin B receptor (ETBR) antagonist with no activity against human type A endothelin receptor (ETA). Vodudeutentan sodium can be incorporated into a controlled systemic release delivery system and can also be selectively combined with an additional antineoplastic agent. Vodudeutentan sodium is applicable to the research of urothelial carcinoma, bladder cancer and renal cell carcinoma[1].
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Vodudeutentan sodium | Vodudeutentan sodium is a deuterated endothelin B receptor (ETBR) antagonist with no activity against human type A endothelin receptor (ETA). Vodudeutentan sodium can be incorporated into a controlled systemic release delivery system and can also be selectively combined with an additional antineoplastic agent. Vodudeutentan sodium is applicable to the research of urothelial carcinoma, bladder cancer and renal cell carcinoma. | |||||||||||||||||||||
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BQ-788 sodium salt | 99.33% | BQ-788 sodium salt is a potent and selective ETB receptor antagonist, inhibiting ET-1 binding to ETB receptors with an IC50 of 1.2 nM in human Girrardi heart cells. | ||||||||||||||||||||
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