FR139317
FR139317 (PD 147953) is a selective ETA receptor antagonist. FR139317 inhibits cerebral activation by intraventricular endothelin-1 in conscious rats. FR139317 also ameliorates cerebral vasospasm in dogs.
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- CAS. Nr.: 142375-60-8
- Formel: C33H44N6O5
- Molecular Weight:604.74
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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ETA |
Chemical Information
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CAS. Nr. 142375-60-8
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Molecular Weight 604.74
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Formel C33H44N6O5
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SMILES
O=C(O)[C@@H](CC1=NC=CC=C1)NC([C@@H](CC2=CN(C)C3=CC=CC=C23)NC([C@H](CC(C)C)NC(N4CCCCCC4)=O)=O)=O
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Synonyms
PD 147953
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Gross PM, et al. FR139317, a specific ETA-receptor antagonist, inhibits cerebral activation by intraventricular endothelin-1 in conscious rats. Neuropharmacology. 1994 Oct;33(10):1155-66. [Content Brief]
[2]. Nirei H, et al. An endothelin ETA receptor antagonist, FR139317, ameliorates cerebral vasospasm in dogs. Life Sci. 1993;52(23):1869-74. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
FR139317 Related Classifications
HY-102092 Related Classifications
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