2374122-43-5

PROTAC IRAK4 degrader-3 Chemical Structure
2374122-43-5

Chemical Structure

PROTAC IRAK4 degrader-3

  • CAS No.: 2374122-43-5
  • Formula:C57H68FN11O8S
  • Molecular Weight:1086.28

IUPAC Name: 1-(((2S,3S,4S)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl)methoxy)-4-(3-(9-(5-(((R)-1-((2R,4S)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)carbamoyl)pyrimidin-2-yl)-3,9-diazaspiro[5.5]undecan-3-yl)prop-1-yn-1-yl)-7-methoxyisoquinoline-6-carboxamide

InChIKey: VCCDOPPWOSIMCD-HCDYCOHBSA-N

SMILES: CC[C@H]([C@@H](C(N1)=O)F)[C@H]1COC2=NC=C(C#CCN3CCC4(CCN(C5=NC=C(C(N[C@H](C(C)(C)C)C(N6[C@H](C[C@@H](C6)O)C(NCC7=CC=C(C8=C(N=CS8)C)C=C7)=O)=O)=O)C=N5)CC4)CC3)C9=C2C=C(OC)C(C(N)=O)=C9

Biological Activity: PROTAC IRAK4 degrader-3 is a PROTAC-induced IRAK4 degrader based on von Hippel-Lindau[1].

Cat. No. Product Name Purity Description Pricing
HY-135382A
PROTAC IRAK4 degrader-3 98.24% PROTAC IRAK4 degrader-3 is a PROTAC-induced IRAK4 degrader based on von Hippel-Lindau.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References