2393-59-1
Chemical Structure
β-Muricholic acid
- CAS No.: 2393-59-1
- Formula:C24H40O5
- Molecular Weight:408.57
IUPAC Name: (R)-4-((3R,5R,6S,7R,8S,9S,10R,13R,14S,17R)-3,6,7-trihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid
InChIKey: DKPMWHFRUGMUKF-CRKPLTDNSA-N
SMILES: C[C@H](CCC(O)=O)[C@H]1CC[C@@]2([H])[C@]3([H])[C@@H](O)[C@@H](O)[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C
Biological Activity: β-Muricholic acid is a potent and orally active biliary cholesterol-desaturating agent. β-Muricholic acid prevents cholesterol gallstones. β-Muricholic acid inhibits lipid accumulation. β-Muricholic acid has the potential for the research of nonalcoholic fatty liver disease (NAFLD)[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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β-Muricholic acid | 99.92% | β-Muricholic acid is a potent and orally active biliary cholesterol-desaturating agent. β-Muricholic acid prevents cholesterol gallstones. β-Muricholic acid inhibits lipid accumulation. β-Muricholic acid has the potential for the research of nonalcoholic fatty liver disease (NAFLD). | ||||||||||||||||||||
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β-Muricholic acid (Standard) | 99.74% | Deracoxib (Standard) is the analytical standard of Deracoxib. This product is intended for research and analytical applications. 0 | ||||||||||||||||||||
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β-Muricholic acid-d5 | β-Muricholic acid-d5 is the deuterium labeled β-Muricholic acid. | |||||||||||||||||||||
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β-Muricholic acid-d4 | 99.1% | β-Muricholic acid-d4 is the deuterium labeled β-Muricholic acid. | ||||||||||||||||||||
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References
- [1]. Takada S, et al. Stress can attenuate hepatic lipid accumulation via elevation of hepatic β-muricholic acid levels in mice with nonalcoholic steatohepatitis. Lab Invest. 2021 Feb;101(2):193-203. [Content Brief]
- [2]. Wang DQ, et al. Effect of beta-muricholic acid on the prevention and dissolution of cholesterol gallstones in C57L/J mice. J Lipid Res. 2002 Nov;43(11):1960-8. [Content Brief]
