α-Muricholic acid
Based on 1 publication(s) in Google Scholar
α-Muricholic acid is the most abundant primary bile acid in rodents.
For research use only. We do not sell to patients.
- Purity: 99.90%
- CAS No.: 2393-58-0
- Formula: C24H40O5
- Molecular Weight:408.57
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) α-Muricholic acid
MoreAll Endogenous Metabolite Isoforms
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Biological Activity
In the context of primary bile acid, α-Muricholic acid is greatly reduced in high-fat diet (HFD)-soybean protein isolate (SPI) mice compared to the HFD controls[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2393-58-0
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Appearance Solid
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Molecular Weight 408.57
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Formula C24H40O5
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Color White to off-white
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SMILES
C[C@@]([C@]1([H])[C@H](O)[C@H]2O)(CC[C@@H](O)C1)[C@]3([H])[C@]2([H])[C@@](CC[C@]4([H])[C@H](C)CCC(O)=O)([H])[C@]4(C)CC3
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Nature
2025 Jul;643(8070):192-200. PMID: 39695227
Solvent & Solubility
DMF : 30 mg/mL (73.43 mM; Need ultrasonic and warming)
DMSO : 20 mg/mL (48.95 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Eyssen HJ, et al. Sulfate bile acids in germ-free and conventional mice. Eur J Biochem. 1976 Jul 15;66(3):507-14. [Content Brief]
[2]. Watanabe K, et al. Dietary soybean protein ameliorates high-fat diet-induced obesity by modifying the gut microbiota-dependent biotransformation of bile acids. PLoS One. 2018 Aug 13;13(8):e0202083. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / DMF | 1 mM | 2.4476 mL | 12.2378 mL | 24.4756 mL | 61.1890 mL |
| 5 mM | 0.4895 mL | 2.4476 mL | 4.8951 mL | 12.2378 mL | |
| 10 mM | 0.2448 mL | 1.2238 mL | 2.4476 mL | 6.1189 mL | |
| 15 mM | 0.1632 mL | 0.8159 mL | 1.6317 mL | 4.0793 mL | |
| 20 mM | 0.1224 mL | 0.6119 mL | 1.2238 mL | 3.0595 mL | |
| 25 mM | 0.0979 mL | 0.4895 mL | 0.9790 mL | 2.4476 mL | |
| 30 mM | 0.0816 mL | 0.4079 mL | 0.8159 mL | 2.0396 mL | |
| 40 mM | 0.0612 mL | 0.3059 mL | 0.6119 mL | 1.5297 mL | |
| DMF | 50 mM | 0.0490 mL | 0.2448 mL | 0.4895 mL | 1.2238 mL |
| 60 mM | 0.0408 mL | 0.2040 mL | 0.4079 mL | 1.0198 mL |
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