2407829-65-4
2407829-65-4
Chemical Structure
CRBN modulator-1
- CAS No.: 2407829-65-4
- Formula:C17H12N2O5
- Molecular Weight:324.29
IUPAC Name: 2-(2,6-dioxopiperidin-3-yl)-5-hydroxy-1H-benzo[de]isoquinoline-1,3(2H)-dione
InChIKey: WGTKYDFLBDSIPX-UHFFFAOYSA-N
SMILES: O=C1N(C(CC2)C(NC2=O)=O)C(C3=CC(O)=CC4=CC=CC1=C34)=O
Biological Activity: CRBN modulator-1, a Thalidomide analog and a CRBN modulator extracted from WO2020006262A1, compound 10, has an IC50 of 3.5 μM and a Ki of 0.98 μM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CRBN modulator-1 | 98.00% | CRBN modulator-1, a Thalidomide analog and a CRBN modulator extracted from WO2020006262A1, compound 10, has an IC50 of 3.5 μM and a Ki of 0.98 μM. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.84
HY-W998253CRBN ligand-678 -
Similarity Score 0.81
HY-W998256DGY-02-126-O-C-COOH -
Similarity Score 0.77
HY-W998254CRBN ligand-679 -
Similarity Score 0.75
HY-174880CRBN ligand-8-O-C6-NH2 -
Similarity Score 0.74
HY-W998255CRBN ligand-680 -
Similarity Score 0.72
HY-139549Thalidomide-benzo -
Similarity Score 0.71
HY-23095RThalidomide-5-OH (Standard) -
Similarity Score 0.71
HY-W457158(S)-Thalidomide-5-OH -
Similarity Score 0.67
HY-103596Thalidomide-4-OH -
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