2409783-34-0
2409783-34-0
Chemical Structure
Gatuzosiran
Synonym(s): GSK4532990; ARO-HSD
- CAS No.: 2409783-34-0
- Formula:C493H653F11N163O311P43S7
- Molecular Weight:15603.70
SMILES: [Gatuzosiran]
Biological Activity: Gatuzosiran (GSK4532990; ARO-HSD) is a GalNAc-conjugated siRNA that inhibits HSD17B13. Gatuzosiran downregulates HSD17B13 mRNA and protein levels. Gatuzosiran improves noninvasive biomarkers of liver function enzymes, liver fibrosis, and steatosis associated with metabolic dysfunction-associated steatohepatitis. Gatuzosiran can be used for research on metabolic dysfunction-associated steatohepatitis[1].
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Gatuzosiran | 98.89% | Gatuzosiran (GSK4532990; ARO-HSD) is a GalNAc-conjugated siRNA that inhibits HSD17B13. Gatuzosiran downregulates HSD17B13 mRNA and protein levels. Gatuzosiran improves noninvasive biomarkers of liver function enzymes, liver fibrosis, and steatosis associated with metabolic dysfunction-associated steatohepatitis. Gatuzosiran can be used for research on metabolic dysfunction-associated steatohepatitis. | ||||||||||||||||||||
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