2414053-06-6
2414053-06-6
Chemical Structure
AChE/HDAC-IN-1
- CAS No.: 2414053-06-6
- Formula:C26H27ClN4O3
- Molecular Weight:478.97
IUPAC Name: (E)-N-(3-((6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino)propyl)-4-(3-(hydroxyamino)-3-oxoprop-1-en-1-yl)benzamide
InChIKey: WNEPUZILCBHSEU-MDWZMJQESA-N
SMILES: O=C(NCCCNC1=C(CCCC2)C2=NC3=CC(Cl)=CC=C31)C4=CC=C(/C=C/C(NO)=O)C=C4
Biological Activity: COX-2-IN-23 (compound A10) is a potent both AChE and HDAC inhibitor with IC50 values of 0.12 and 0.23 nM. COX-2-IN-23 exhibits antioxidant activity and metal chelating properties. COX-2-IN-23 can be used in alzheimer's disease research[1].
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AChE/HDAC-IN-1 | COX-2-IN-23 (compound A10) is a potent both AChE and HDAC inhibitor with IC50 values of 0.12 and 0.23 nM. COX-2-IN-23 exhibits antioxidant activity and metal chelating properties. COX-2-IN-23 can be used in alzheimer's disease research. | |||||||||||||||||||||
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References
Keywords
