2417098-53-2
2417098-53-2
Chemical Structure
PI3Kα-IN-7
- CAS No.: 2417098-53-2
- Formula:C17H22N8O2S
- Molecular Weight:402.47
IUPAC Name: N-((2,4-dimorpholinothieno[3,2-d]pyrimidin-6-yl)methyl)-1H-1,2,4-triazol-3-amine
InChIKey: FUFBBCHWTVTMIP-UHFFFAOYSA-N
SMILES: C1(NCC2=CC(N=C(N3CCOCC3)N=C4N5CCOCC5)=C4S2)=NNC=N1
Biological Activity: PI3Kα-IN-7 (Compound A12) is a potent PI3Kα inhibitor. PI3Kα-IN-7 also inhibits PI3Kβ. PI3Kα-IN-7 decreases cancer cells mitochondrial membrane potential and induces apoptosis[1].
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PI3Kα-IN-7 | PI3Kα-IN-7 (Compound A12) is a potent PI3Kα inhibitor. PI3Kα-IN-7 also inhibits PI3Kβ. PI3Kα-IN-7 decreases cancer cells mitochondrial membrane potential and induces apoptosis. | |||||||||||||||||||||
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