2432825-93-7
2432825-93-7
Chemical Structure
HDAC8-IN-3
- CAS No.: 2432825-93-7
- Formula:C18H12N4O3S2
- Molecular Weight:396.44
IUPAC Name: (E)-N-(benzo[d]thiazol-2-yl)-2-(2,4-dioxo-5-(pyridin-2-ylmethylene)thiazolidin-3-yl)acetamide
InChIKey: UZIRFWMKGFFXMC-NTEUORMPSA-N
SMILES: O=C(NC1=NC2=CC=CC=C2S1)CN(C/3=O)C(SC3=C\C4=NC=CC=C4)=O
Biological Activity: HDAC8-IN-3 (compound P19) is a potent HDAC8 inhibitor with IC50 value of 9.3 μM and produces thermal stabilization. HDAC8-IN-3 has cytotoxicity and induces apoptosis in leukemic cell lines[1].
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HDAC8-IN-3 | HDAC8-IN-3 (compound P19) is a potent HDAC8 inhibitor with IC50 value of 9.3 μM and produces thermal stabilization. HDAC8-IN-3 has cytotoxicity and induces apoptosis in leukemic cell lines. | |||||||||||||||||||||
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