2444837-63-0
Chemical Structure
BRD 4354 ditrifluoroacetate
- CAS No.: 2444837-63-0
- Formula:C25H25ClF6N4O5
- Molecular Weight:610.93
IUPAC Name: 5-chloro-7-((4-ethylpiperazin-1-yl)(pyridin-3-yl)methyl)quinolin-8-ol bis(2,2,2-trifluoroacetate)
InChIKey: LTJCVYFLZPEFLV-UHFFFAOYSA-N
SMILES: OC1=C2N=CC=CC2=C(Cl)C=C1C(N3CCN(CC)CC3)C4=CC=CN=C4.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F
Biological Activity: BRD 4354 (ditrifluoroacetate) is a moderately potent inhibitor of HDAC5 and HDAC9, with IC50s of 0.85 and 1.88 μM, respectively[1].
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BRD 4354 ditrifluoroacetate | BRD 4354 (ditrifluoroacetate) is a moderately potent inhibitor of HDAC5 and HDAC9, with IC50s of 0.85 and 1.88 μM, respectively. | |||||||||||||||||||||
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Keywords