2459938-28-2
2459938-28-2
Chemical Structure
COX-2/PI3K-IN-2
- CAS No.: 2459938-28-2
- Formula:C16H17N5O2
- Molecular Weight:311.34
IUPAC Name: (Z)-1-((1H-imidazol-1-yl)methyl)-3-(2-oxo-1-propylindolin-3-ylidene)urea
InChIKey: AHZVMEXLIIBRBY-RGEXLXHISA-N
SMILES: O=C(/N=C1C(N(CCC)C2=C\1C=CC=C2)=O)NCN3C=CN=C3
Biological Activity: COX-2/PI3K-IN-2 (compound 5f) is a potent PI3K inhibitor with IC50 value of 2.78 nM. COX-2/PI3K-IN-2 is a selective COX-2 inhibitor with Ki value of 3.02 nM. COX-2/PI3K-IN-2 shows anti-inflammatory and anti-cancer properties[1].
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COX-2/PI3K-IN-2 | COX-2/PI3K-IN-2 (compound 5f) is a potent PI3K inhibitor with IC50 value of 2.78 nM. COX-2/PI3K-IN-2 is a selective COX-2 inhibitor with Ki value of 3.02 nM. COX-2/PI3K-IN-2 shows anti-inflammatory and anti-cancer properties. | |||||||||||||||||||||
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