247044-67-3
247044-67-3
Chemical Structure
Insulin β Chain Peptide (15-23)
- CAS No.: 247044-67-3
- Formula:C44H72N12O13S
- Molecular Weight:1009.18
InChIKey: CPSZWYPVFBXING-PVKJLKLCSA-N
SMILES: O=C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CS)C(NCC(N[C@@H](CCC(O)=O)C(N[C@@H](CCCNC(N)=N)C(NCC(O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC(C)C)N
Biological Activity: Insulin β Chain Peptide (15-23) is one of the earliest antigenic epitopes to which CD8 T-cells respond[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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Insulin β Chain Peptide (15-23) | 95.68% | Insulin β Chain Peptide (15-23) is one of the earliest antigenic epitopes to which CD8 T-cells respond. | ||||||||||||||||||||
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References
- [1]. Amrani A, et al. Progression of autoimmune diabetes driven by avidity maturation of a T-cell population. Nature. 2000;406(6797):739-742. [Content Brief]
- [2]. Takaki T, et al. Requirement for both H-2Db and H-2Kd for the induction of diabetes by the promiscuous CD8+ T cell clonotype AI4. J Immunol. 2004;173(4):2530-2541. [Content Brief]
- [3]. Wong FS, et al. Activation of insulin-reactive CD8 T-cells for development of autoimmune diabetes. Diabetes. 2009 May;58(5):1156-64. [Content Brief]
Keywords
