2471982-20-2
2471982-20-2
Chemical Structure
CU-115
- CAS No.: 2471982-20-2
- Formula:C21H11F7INO2
- Molecular Weight:569.21
IUPAC Name: N-(4-(3,5-bis(trifluoromethyl)phenoxy)phenyl)-2-fluoro-6-iodobenzamide
InChIKey: QYSLCRYVUJORPX-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(OC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)C=C1)C3=C(I)C=CC=C3F
Biological Activity: CU-115 is a potent TLR8 antagonist (IC50=1.04 µM), and shows selective for TLR8 over TLR7 (IC50=>50 µM). CU-115 decreases TNF-α and IL-1β production activated by R-848 in THP-1 cells[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CU-115 | 99.63% | CU-115 is a potent TLR8 antagonist (IC50=1.04 µM), and shows selective for TLR8 over TLR7 (IC50=>50 µM). CU-115 decreases TNF-α and IL-1β production activated by R-848 in THP-1 cells. | ||||||||||||||||||||
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References
Keywords
