AFG210
AFG210 is a potent multi-target kinase inhibitor that primarily inhibits Abl kinase (IC50=330 nM), and also has inhibitory effects on other kinases such as B-Raf, C-Raf, FGFR-1, RET and VEGF receptors. AFG210 can be used to study chronic myeloid leukemia and other diseases with abnormal activation of Abl kinase.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 228400-22-4
- Formel: C19H14F3N3O2
- Molecular Weight:373.33
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 228400-22-4
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Molecular Weight 373.33
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Formel C19H14F3N3O2
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SMILES
O=C(NC1=CC=C(OC2=CC=NC=C2)C=C1)NC3=CC=CC(C(F)(F)F)=C3
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
AFG210 Related Classifications
HY-18817 Related Classifications
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