2473270-96-9
2473270-96-9
Chemical Structure
Thalidomide-O-amido-C11-COOH
- CAS No.: 2473270-96-9
- Formula:C27H35N3O8
- Molecular Weight:529.58
InChIKey: CSYVEJMBYGPRAJ-UHFFFAOYSA-N
SMILES: O=C(CCCCCCCCCCCNC(COC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O)=O)O
Biological Activity: Thalidomide-O-amido-C11-COOH (compound IMiD acid 1) is an E3 ligase ligand and linker CRBN (Cereblon) conjugate. Thalidomide-O-amido-C11-COOH can be used to synthesize PROTAC that target the degradation of DOT1L[1].
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Thalidomide-O-amido-C11-COOH | Thalidomide-O-amido-C11-COOH (compound IMiD acid 1) is an E3 ligase ligand and linker CRBN (Cereblon) conjugate. Thalidomide-O-amido-C11-COOH can be used to synthesize PROTAC that target the degradation of DOT1L. | |||||||||||||||||||||
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