24769-56-0
Chemical Structure
PGE-M
Synonym(s): tetranor-PGEM
- CAS No.: 24769-56-0
- Formula:C16H24O7
- Molecular Weight:328.36
IUPAC Name: 8-((1R,2R,5R)-2-(2-carboxyethyl)-5-hydroxy-3-oxocyclopentyl)-6-oxooctanoic acid
InChIKey: ZJAZCYLYLVCSNH-JHJVBQTASA-N
SMILES: O[C@H]1[C@@H]([C@H](C(C1)=O)CCC(O)=O)CCC(CCCCC(O)=O)=O
Biological Activity: PGE-M (tetranor-PGEM) is a metabolite of Prostaglandin E2 (HY-101952) and also an inflammatory biomarker. Urinary PGE-M is a potential biomarker for detecting advanced colorectal tumors. PGE-M can be used in studies related to colorectal cancer, obesity, aging and breast cancer[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PGE-M | 99.9% | PGE-M (tetranor-PGEM) is a metabolite of Prostaglandin E2 (HY-101952) and also an inflammatory biomarker. Urinary PGE-M is a potential biomarker for detecting advanced colorectal tumors. PGE-M can be used in studies related to colorectal cancer, obesity, aging and breast cancer. | ||||||||||||||||||||
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tetranor-PGEM-d6 | 99.9% | tetranor-PGEM-d6 is the deuterium labeled tetranor-PGEM. | ||||||||||||||||||||
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- [1]. Johnson JC, et al. Urine PGE-M: A metabolite of prostaglandin E2 as a potential biomarker of advanced colorectal neoplasia. Clin Gastroenterol Hepatol. 2006;4(11):1358-1365. [Content Brief]
- [2]. Morris PG, et al. Increased levels of urinary PGE-M, a biomarker of inflammation, occur in association with obesity, aging, and lung metastases in patients with breast cancer. Cancer Prev Res (Phila). 2013;6(5):428-436. [Content Brief]
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