24769-56-0
Chemical Structure
PGE-M
Synonym(s): tetranor-PGEM
- CAS No.: 24769-56-0
- Formula:C16H24O7
- Molecular Weight:328.36
IUPAC Name: 8-((1R,2R,5R)-2-(2-carboxyethyl)-5-hydroxy-3-oxocyclopentyl)-6-oxooctanoic acid
InChIKey: ZJAZCYLYLVCSNH-JHJVBQTASA-N
SMILES: O[C@H]1[C@@H]([C@H](C(C1)=O)CCC(O)=O)CCC(CCCCC(O)=O)=O
Biological Activity:
PGE-M (tetranor-PGEM) is a metabolite of Prostaglandin E2 (HY-101952) and also an inflammatory biomarker. Urinary PGE-M is a potential biomarker for detecting advanced colorectal tumors. PGE-M can be used in studies related to colorectal cancer, obesity, aging and breast cancer[1][2].
The product specifications provided below refer solely to the active content of PGE-M.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PGE-M | 99.9% | PGE-M (tetranor-PGEM) is a metabolite of Prostaglandin E2 (HY-101952) and also an inflammatory biomarker. Urinary PGE-M is a potential biomarker for detecting advanced colorectal tumors. PGE-M can be used in studies related to colorectal cancer, obesity, aging and breast cancer. The product specifications provided below refer solely to the active content of PGE-M. |
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tetranor-PGEM-d6 | 99.9% | tetranor-PGEM-d6 is the deuterium labeled tetranor-PGEM. The product specifications provided below refer solely to the active content of tetranor-PGEM-d6. |
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Similarity Score 0.99
HY-126986STetranor-PGDM-d6 -
Similarity Score 0.99
HY-126986Tetranor-PGDM -
Similarity Score 0.89
HY-17069813,14-Dihydro-15-keto-tetranor prostaglandin E2 -
Similarity Score 0.89
HY-11608313,14-Dihydro-15-keto-tetranor prostaglandin D2 -
Similarity Score 0.83
HY-118163tetranor-PGFM -
Similarity Score 0.79
HY-13759113,14-Dihydro-15-keto-PGE1 -
Similarity Score 0.79
HY-16337313,14-Dihydro-15-keto prostaglandin D1 -
Similarity Score 0.76
HY-1146875,7-Dihydroxy-11-ketotetranorprostanoic acid -
Similarity Score 0.76
HY-16880113,14-Dihydro-15-keto-tetranor prostaglandin F1β -
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References
- [1]. Johnson JC, et al. Urine PGE-M: A metabolite of prostaglandin E2 as a potential biomarker of advanced colorectal neoplasia. Clin Gastroenterol Hepatol. 2006;4(11):1358-1365. [Content Brief]
- [2]. Morris PG, et al. Increased levels of urinary PGE-M, a biomarker of inflammation, occur in association with obesity, aging, and lung metastases in patients with breast cancer. Cancer Prev Res (Phila). 2013;6(5):428-436. [Content Brief]
