2489320-03-6
Chemical Structure
Protein kinase D inhibitor 1
- CAS No.: 2489320-03-6
- Formula:C19H21N7
- Molecular Weight:347.42
IUPAC Name: 3-(1H-indol-3-yl)-1-(piperidin-4-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
InChIKey: GTWNYADDKACXSW-UHFFFAOYSA-N
SMILES: NC1=C2C(N(CC3CCNCC3)N=C2C4=CNC5=C4C=CC=C5)=NC=N1
Biological Activity: Protein kinase D inhibitor 1 (compound 17m) is a pan-PKD inhibitor, with IC50 values ranging from 17 to 35 nM. Protein kinase D inhibitor 1 inhibits PKD-dependent cortactin phosphorylation[1].
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Protein kinase D inhibitor 1 | Protein kinase D inhibitor 1 (compound 17m) is a pan-PKD inhibitor, with IC50 values ranging from 17 to 35 nM. Protein kinase D inhibitor 1 inhibits PKD-dependent cortactin phosphorylation. | |||||||||||||||||||||
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Keywords