2490589-08-5
Chemical Structure
sEH/AChE-IN-1
- CAS No.: 2490589-08-5
- Formula:C29H31ClF3N5O3
- Molecular Weight:590.04
IUPAC Name: 1-(1-(3-((6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino)propanoyl)piperidin-4-yl)-3-(4-(trifluoromethoxy)phenyl)urea
InChIKey: WTPMKFXZAUAECV-UHFFFAOYSA-N
SMILES: ClC1=CC2=C(C(NCCC(N3CCC(CC3)NC(NC4=CC=C(C=C4)OC(F)(F)F)=O)=O)=C5C(CCCC5)=N2)C=C1
Biological Activity: sEH/AChE-IN-1 (Compound 12a) is a dual inhibitor of the enzymes soluble epoxide hydrolase (sEH) and acetylcholinesterase (AChE). sEH/AChE-IN-1 provides cumulative effects against neuroinflammation and memory impairment. sEH/AChE-IN-1 has the potential for the research of Alzheimer's disease (AD)[1].
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sEH/AChE-IN-1 | sEH/AChE-IN-1 (Compound 12a) is a dual inhibitor of the enzymes soluble epoxide hydrolase (sEH) and acetylcholinesterase (AChE). sEH/AChE-IN-1 provides cumulative effects against neuroinflammation and memory impairment. sEH/AChE-IN-1 has the potential for the research of Alzheimer's disease (AD). | |||||||||||||||||||||
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Keywords
